United States Patent 7,572,449
Hill , et al. August 11, 2009

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Vaccine against Yersinia comprising one or two antibodies, one specific for Yersinia pestis F1-antigen and the other one for Yersinia pestis V-antigen


Abstract
The use of (i) an antibody specific for Yersinia pestis F1-antigen, or a binding fragment thereof, or (ii) an antibody specific for Yersinia pestis V-antigen, or a binding fragment thereof, or a combination of (i) and (ii), in the production of a medicament for the treatment of infection by Yersinia pestis. It has been found that such treatments are effective therapies for Yersinia pestis infection. In addition, the combination produces a synergistic effect when used prophylactically.


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Inventors: Hill; James (Salisbury, GB), Williamson; Ethel Diane (Salisbury, GB), Titball; Richard William (Salisbury, GE)
Assignee: The Secretary of State for Defense in Her Britannic Majesty's Government of the United Kingdom of Great Britain and Northern Ireland (GB)
N/A (

Appl. No.: 10/525,057