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What Is The Best Magnesium Supplement?
Magnesium is one of the most important nutrients for human health. I have covered this extensively on my website for years. After reading my articles, many people reach the conclusion that they would like to add a magnesium supplement to their daily regimen. If you go to a local supplement, health food, or online store you will notice there are A TON of different forms of magnesium. These are not all created equal. So, what is the best magnesium supplement for the most health benefits?
The different forms of magnesium are metabolized and have different effects in the body. Some provide negligible effects, some stronger, and some I would consider superior. This is something I observed early on when considering adding a magnesium supplement to my personal line.
The Fundamental Role Of Magnesium
I say magnesium is one of the most important nutrients in the human body all the time and there is a HUGE reason for this. One of the biggest predictors of your overall well-being is your body’s ability to create and utilize energy. From a cellular level, this energy comes in the form of a molecule called ATP (adenosine triphosphate).
Your body is constantly operating within a balance of breaking down and rebuilding itself, a principal called homeostasis. On a very basic level, when you are breaking down faster than you are rebuilding, you have disease. When you are rebuilding as quickly as you are breaking down, you are thriving, adapting, and becoming stronger.
Every cell in your body relies on ATP in order to carry out its function. A fundamental principal of human physiology is that cells cannot effectively utilize ATP unless it is in its activated form, Mg-ATP. Magnesium actually binds to ATP and this important step allows our cells to use it more effectively.
Additionally, magnesium is intricately involved in the biological process of manufacturing ATP, so it could not be more crucial in this regard that you have enough magnesium to provide for the energy making process of almost every cell in your body. This is key in helping to optimize your body’s ability to heal and adapt.
Symptoms Of Deficiency
Magnesium deficiency is often misdiagnosed because it is not easily detected in routine bloodwork. This is because almost all of the body’s magnesium is stored in the bones and organ tissues, particularly in the heart (1). It is estimated that only 1% of our total magnesium can actually be found floating around in the blood.
The organs in your body that require the most ATP include the brain, muscles (heart, digestive tract, skeletal muscle), and the ovaries if you are a woman.
Consequently, some of the most prominent symptoms of magnesium deficiency are brain fog, poor memory, trouble concentrating, muscle cramps/weakness, fibromyalgia, migraines/headaches, anxiety, depression, and PMS.
These are some of the common symptoms, however magnesium is also involved in over 300 different enzymatic processes in the body so symptoms of deficiency may vary widely. Some experts even claim that magnesium deficiency may contribute to over 20 different diagnosable medical conditions (2).
Why We Need More Than We Used To
Although some magnesium can be obtained from the diet, there are a couple important reasons why I often recommend supplementation.
First, modern industrial farming practices have drastically depleted soil of its nutrient content, this means we are likely receiving much less than we used to.
Next, our environment is filled with new chemicals and biological stressors that increase our need for magnesium. These include things like EMF, pesticides, heavy metals, and general chronic stress involved with our chosen lifestyles. All of these things increase stress on our bodies, increase the need for ATP, and rapidly deplete magnesium stores as a consequence.
Supplementing with magnesium will help restore optimal levels to ensure effective energy production. Another cool thing I like about magnesium is that it can also improve your ability to adapt to a stressful lifestyle, similar to common herbal adaptogens.
Top Magnesium Supplement Forms
There are A TON of different types of magnesium that are sold in stores. Many of these simply are not effective and will not do anything beneficial for your health. In fact, some forms of magnesium are not even absorbable by yourdigestive tract.
Below are some of my favorite forms of magnesium and the ones that are the most likely to benefit your health.
Malate
Magnesium malate is magnesium bonded to malic acid. Malic acid is naturally occuring in many foods, especially fruits. This form of magnesium is theorized to be best suited for improving energy-related disorders.
This is thought because malic acid is a key component of the Krebs Cycle. The Krebs Cycle is the biological process that is responsible for manufacturing ATP, AKA energy. This is where magnesium malate may be helpful in conditions such as chronic fatigue or depression.
Animal studies have observed that magnesium malate may provide benefits for blood sugar regulation and magnesium/calcium balance, making it a solid option for supplementation (3).
Glycinate
Magnesium Glycinate (or chelated magnesium) is a compound made up of magnesium and the amino acid glycine. This is thought to be one of the most bioavailable forms of magnesium for supplementation as well as one of the most gut friendly. Many people experience diarrhea with magnesium supplementation so this can be an important consideration.
For clinically diagnosable magnesium deficiency (hypomagnesia), the glycinate or bisglycinate form of magnesium are typically the most recommended for correcting this.
L-Threonate
Magnesium L-threonate (MgT) is a newer form of magnesium with significant implications for mental health. Some preliminary research has highlighted the cognitive boosting ability and potentially even neuroprotective effects againstAlzheimer’s disease (4).
What is so novel about this form of magnesium supplement is that it is the only form shown in animal studies to cross the blood brain barrier. This is important because having this capability allows it to exert its beneficial effects on the brain specifically.
Consequently, this form of magnesium supplement has been shown to improve measures of cognitive abilities such as short and long term memory and learning (5, 6). Additionally, this form of magnesium may be superior for conditions such as depression, anxiety, and brain fog.
In this article, I go over this 2010 study where a MgT supplemented group was able to retain their memory of where a submerged platform was hidden after 24 hours. Both young and old rats in the control group forgot and began randomly searching through the maze and took more than twice as long as the MgT supplemented group. The results of the study showed that old rats saw a 100% improvement in spatial long-term memory and even out performed younger rats who had not used MgT (5).
Citrate
Magnesium Citrate is one of the most commonly used forms of magnesium because it is relatively low cost while also being reasonably bioavailable when consumed orally.
This form of magnesium supplement is unique because it is one of the only ones that is naturally acidic. This is due to it being bound to citric acid, a common food additive that also occurs in citrus fruits.
Two noteable properties of this form of magnesium are its ability to aid in bowel movements as well as potentially help with oxalate metabolism. I often encounter patients who have kidney stones due high levels of dietary oxalates (more on this here) so this may be helpful for them.
While it may be beneficial for someone with kidney stones to supplement with magnesium citrate, I have actually found potassium citrate to be powerful for this. In combination, they may both provide benefits.
Chloride
Adding a chloride to magnesium brings another broad-range support compound to the mix. When these two are broken down in the body, you get the benefits of both magnesium and chloride. Magnesium chloride is the most stable form of magnesium and is especially good for detoxification and for kidney function.
Chloride ions are abundant in the human body. First of all, as an electrolyte, chloride ions help to assure the proper conduction of impulses within the nervous system. They work along with potassium, sodium, calcium, phosphate, and magnesium to assure proper muscle contraction, control blood pressure, and allow for healthy brain function.
Additionally, chloride combines with hydrogen in the gut to produce HCl (stomach acid). Adequate stomach acid is needed to properly digest our foods and to activate intrinsic factor for absorbing Vitamin B12.
Inferior Magnesium Supplement Forms
Forms of magnesium that are often cheap yet offer relatively low bioavailability include the oxide, dihydroxide (milk of magnesia), sulfate, aspartate, and carbonate forms. These forms of magnesium do not absorb well and tend to offer little benefit beyond laxative or antacid properties.
Magnesium Sulfate (also known as epsom salt) may, however, be suitable for absorption through the skin. For a step above, in my opinion, I would recommend these Magnesium Chloride salts for soaking. They are more expensive but likely to be much more beneficial.
Before You Buy a Magnesium Supplement
While there are many forms and many brands of magnesium available on the market that will likely provide you with benefit. There is one consideration that I find critically important however.
As with all supplements, it is important to ensure you are getting yours from a source that tests every batch to ensure you are getting what is on the label and nothing else. This includes things like unwanted toxins, allergens, and heavy metals.
All of my personal line products are pharmaceutical grade, GMP compliant. This means they are produced in strictly monitored facilities who also send batches of their product to third parties for analysis before selling to consumers.
Brain Calm Magnesium
There are many different forms of magnesium and they seem to have slightly different effects in the body. When I decided to add a magnesium supplement to my personal line I wanted it to contain the best forms of magnesium to provide a well-rounded benefit.
Brain Calm Magnesium was the result of this. It contains patented malate, glycinate, and threonate forms of magnesium for maximum neurological and systemic benefits for the body.
I often recommend this supplement for most people as a cost-effective way to boost magnesium levels, increase the body’s resilience to stress, and promote a tranquil and relaxed mental state.
Topical Magnesium Supplement Options
If you are someone with a lot of digestive issues, you may want to consider a topical magnesium. This type of magnesium supplement can be applied directly to the skin and absorbed into your blood stream for increased bioavailability.
This type of magnesium supplement is also great for applying to tense muscles, aches, and pains. For this purpose, I have found that the Ancient Mineralsbrand works the best.
The topical magnesium with MSM is the best for applying to problem areas or as a general magnesium supplement. The combination of magnesium and MSM is powerful for controlling inflammation and strengthening damaged tissues. This form is also very suitable for athletes!
For those who have trouble sleeping at night, Ancient Minerals also carries atopical magnesium with melatonin. For this one I will typically recommend applying one pump to the bottoms of the feet or abdomen 30 minutes to 1 hour before going to bed.
Top Magnesium Foods
While magnesium supplementation is often a great idea, eating the right foods is just as important.
In the video below I go into detail on my favorite dietary sources. For convenience, I have listed my top 12 below.
As a doctor, business owner, husband and father of 3 young children, I encounter a lot of stress on a daily basis. I need my energy and mental clarity to be super sharp to have a good mental and emotional response to things and make good decisions. I also do a lot of writing and need to be creative and innovative with my thoughts and ideas.
The lifestyle habits I engage in and the supplements I take and write about on this website are absolutely vital to helping me be at my best. Magnesium is one of the most important supplements I use on a daily basis.
For optimal performance and great sleep, I use the Brain Calm Magnesium powder. I personally enjoy the Lemon-Lime flavor unless I am fasting and then I use the unflavored version. We also offer a capsule form as many people prefer that over the powder form.
2. Magnesium: An Invisible Deficiency That Could Be Harming Your Health (LINK)
3. Virag, V., May, Z., Kocsis, I., Blazovics, A., & Szentmihalyi, K. (2011). [Effects of magnesium supplementation on calcium and magnesium levels, and redox homeostasis in normolipidemic and food-induced hyperlipidemic rats]. Orv Hetil, 152, 1075–1081. PMID: 21676674
4. Li W, Yu J, Liu Y, et al. Elevation of brain magnesium prevents synaptic loss and reverses cognitive deficits in Alzheimer’s disease mouse model. Mol Brain. 2014 Sep 13;7(1):65. PMID:25213836
5. Slutsky I, Abumaria N, Wu LJ, et al. Enhancement of learning and memory by elevating brain magnesium. Neuron. 2010 Jan 28;65(2):165-77. PMID:20152124
6. Abumaria N, Yin B, Zhang L, et al. Effects of elevation of brain magnesium on fear conditioning, fear extinction, and synaptic plasticity in the infralimbic prefrontal cortex and lateral amygdala. J Neurosci. 2011 Oct 19;31(42):14871-81. PMID:22016520
Joe Tippins found out he had small cell lung cancer in January 2017, and was certain that he would die.
A veterinarian suggested he try a drug for dogs to combat his cancer. The medication, called fenbendazole, is an anti-worm compound used to treat roundworms, hookworms, and other gut parasites, primarily in dogs.
Recent studies in a growing number of medical journals suggest that anti-worm drugs may have cancer-fighting properties.
Joe decided to take a chance because with three months to live, he had nothing to lose. He was diagnosed with late-stage lung cancer in late 2016, and by 2017 it had spread throughout his entire body – his liver, pancreas, bladder, stomach, neck, and bones. He was given three months to live, and was worried he would not get to meet his first grandson.
Remarkably, today, Joe is cancer free. He attributes his current status to the dog de-worming drug he took while also enrolled in a clinical trial.
When Joe found out he had cancer, doctors at MD Anderson Cancer Center in Texas told him they weren’t going to give up on him. They put him in a clinical trial that wouldn’t save him, but might give him about a year to live. A year sounded better than three months (and he might get to meet his first grandson) so he decided to go for it.
During the trial, Joe was browsing an online forum for Oklahoma State University, his alma mater, and he saw a post that caught his eye. It said:
If you have cancer or know someone who does, give me a shout.1
Joe, who looked like a skeleton with skin hanging off of it, reached out and contacted the poster, who was a veterinarian. He discovered that scientists had inadvertently found out that a dog de-worming drug seemed to combat many cancers in mice. The scientist that had conducted the research, as it turned out, had stage 4 brain cancer, and had been given the same prognosis Joe had been given, according to the vet.
The veterinarian had told the scientist about fenbendazole, a de-worming drug for dogs, which had shown cancer-fighting properties in cell studies. She started taking the dog pills, and within six weeks, as the vet told it, the scientist’s cancer was gone.
Joe told KOCO 5 News that he placed an order for fenbenazole, which cost him just $5 a week. He said his insurance company had spent $1.2 million on him with conventional means.
According to a study published in Nature, fenbenazole basically starves cancer cells and kills them. And, it is already in production, cheaper, and, according to cell studies and reports from people who have tried it, not very toxic, especially compared to chemo and immunotherapies. But, having said all that, it was a risk.
Joe remained in the clinical trial (it is not clear what therapy he received in the trial) and added vitamin E, CBD, bioavailable curcumin and, of course, the de-worming medicine. He did not mention the latter to his doctors.
The difference between Joe’s PET scans in January of 2017 and in May of 2017 was unbelievable. And in May, Joe got to meet his first grandchild, Luke.
Two-and-a-half weeks later, he had another PET scan. Joe was dumbfounded, and so was his oncologist. He said:
Three months earlier…There was cancer in my body from head to toe. And it was a terrifyingly dangerous metastasis that leaves virtually 100% of its victims dead within 3 months. Here I was 3 months later and the PET scan was completely dark……void of any light…..anywhere.1
Joe said his doctor, who was still unaware of the dog medicine, told him:
We don’t quite know what to make of this as you are the only patient on the clinical trial with this kind of response.1
In September 2017, Joe went for yet another scan. And he was still cancer free. He finally decided to tell his doctor about the dog medicine.
Joe said there was no way at that point to prove that it was the de-worming drug that made his cancer vanish, but his doctor did tell him that he was an ‘outlier’ of the trial. His final scan was taken in January of 2018, with a follow-up appointment that April. He said that his oncologist kicked him out of the cancer center because Joe had no cancer to treat.
Joe realizes that his results seem too good to be true. However, he says he has heard over forty similar success stories using the dog medicine.
His results were good enough to catch the attention of the president of the Oklahoma Medical Research Foundation, Dr Stephen Prescott, who told KOCO:
I’m usually skeptical, and I was and maybe still am about this one, but there’s interesting background on this.1
According to KOCO, Dr Prescott and Joe are currently working on a case study report. Joe is cautious to note that he’s not a doctor, and is only one man with limited resources, adding:
I am not prescribing medicine and I am not qualified to give advice on medical treatments. BUT…..I am qualified to tell my story to as many people as possible.1
Erin Elizabeth is a long time activist with a passion for the healing arts, working in that arena for a quarter century. Her site HealthNutNews.com is barely 4 years old, but cracked the top 20 Natural Health sites worldwide. She is an author, public speaker, and has recently done some TV and film programs for some of her original work which have attracted international media coverage. Erin was the recipient for the Doctors Who Rock "Truth in Journalism award for 2017. You can get Erin’s free e-book here and also watch a short documentary on how she overcame vaccine injuries, Lyme disease, significant weight gain, and more. Follow Erin on Facebook, Twitter, and Instagram.P.S. You can subscribe to her Youtube Channel for breaking news, television appearances and more.