Saturday, September 23, 2017
Friday, September 22, 2017
How to boost your adrenals
In just one day, I can feel like I’m on a crazy ride of opposites: stress and relaxation, happiness and sadness, bursts of energy and extreme fatigue. It is amazing how many emotions and physiological jolts I experience in 24 hours…sound familiar?!
Your body is extremely resilient and adaptive under a variety of conditions, but it cannot accomplish the demands of whatever happens to be thrown its way without proper nutrition and physiological support. Stress and fatigue tend to be a huge struggle for just about everyone, causing detrimental effects to your physical and mental health.
Businesses are jumping on taking advantage of the growing number of caffeine and sugar addictions, hence the ability to find at least one, if not two, coffee shops on just about every block. The endless supply of sugar filled lattes and carb loaded treats give your body and mind a boost of energy and a quick fix, and then abruptly leave you craving more and further exhausted.
Your body has a surprising ability to manage stress, yet on the inside your body is pleading for rest. Chronically elevated cortisol levels can affect every system in your body like burnt out adrenal glands, overstressed digestive tract, rapid aging, anxiety, cancer, chronic fatigue, common cold, hormone imbalance, irritable bowel disease, auto-immune disorders, thyroid conditions, and weight loss resistance.
Instead of just reaching for a short-lived remedy, I want to introduce an effective, long-term alternative for your body that will increase your resistance to stress, anxiety, and fatigue.
Adaptogens are a class of plants used for their healing abilities of balancing, restoring, and protecting your body as a whole – little miracles I call them.
Adaptogens were granted their name because of their distinctive ability to ‘adapt’ their function according to your body’s needs. An adaptogen does not have a specific action, nor target a certain body region, rather it benefits the body as a whole, being able to respond to any influence or stressor that it needs to.
These rejuvenating plants improve and recharge the health of your adrenal glands, counteracting the harmful effects of stress. Cells are accessed more energy and the ability to eliminate toxic byproducts of the metabolic process to help the body use oxygen more efficiently. More cellular energy in combination with boosting the adrenal glands strengthens the body’s ability to cope with stress, anxiety, and fatigue – calming you down and boosting you up simultaneously.
While prescription drugs remain in your system and influence multiple organs, once an adaptogen has completed its job, those herbs are eliminated or absorbed into the body without any side effects. Adaptogens work slowly and gently, contrasting the instantaneous gratification of the caffeine cycle, you must be patient because they work subtly but the benefits are undeniable and long lasting.
Here are 6 of my favorite adaptogens:
The easer of anxiety, depression and sleep issues. Ashwaganda has immuno-modulating effects that boost and regulate the immune system and lower cortisol levels. You can take Ashwaganda is supplement form, I recommend Organic India Ashwaganda.
Increases the amount of anti-stress compounds our bodies use to prevent and repair stress-related damage. By reducing the ability of stress hormones like cortisol to bind to receptors, astralagus boosts immunity and shields the body from the effects of stress. I recommend adding 20-30 drops of Astralagus Root Extract to your morning juices or smoothies.
3. Cordycep Mushroom
Funguses with antioxidant properties include Reishi, Shiitake, and Maitake mushrooms. Each have adaptogenic, anti-tumor, and immune enhancing properties. You can easily add a scoop of Cordycep powder to Smoothies, I like Mushroom Matrix Organic Cordycep.
4. Holy Basil (Tulsi)
Referred to as the “elixir of anti-aging,” holy basil helps fight fatigue and stress, boosts the immune system, and regulates blood sugar, blood pressure, and hormone levels. My favorite way to enjoy Holy Basil is in a warm cup of Tulsi Tea by Organic India.
5. Rhodiola (Golden Root)
Contains the phytochemical salisdroside which helps resist anxiety and aging. Other benefits include suppression of the production of cortisol, increased levels of stress-resistant proteins, restoration of normal patterns of eating and sleeping after stress, resistance to mental and physical fatigue, and protection against oxidative stress, heat stress, radiation and toxic chemicals. Additional research has shown this adaptogen can protect the heart and liver, increase use of oxygen, improve memory and longevity, as well as aid in weight loss. One of the easiest ways to take is in supplement form, I suggest Gaia Herbs Rhodiola.
Used for preventing early aging which counteracts cortisol’s aging effects. Schisandra is also used to increase lifespan, increase resistance to disease, increase energy and physical performance, normalize blood sugar, and stimulate the immune system. You can easily take as a supplement, like these Planetary Herb Adrenal Complex or add into shakes, juices, smoothies with Dragon Herb’s Goji & Shizandra.
Incorporating adaptogens into your daily regimen will allow you to feel a huge improvement in your energy and stress levels, a bigger improvement than you could think some small plants can do.
Wednesday, September 20, 2017
Stop Using Vaseline Immediately! 4 reasons you should never put petroleum jelly on your skin
Petroleum Jelly, the main ingredient in Vaseline®, is often used in beauty products and even on its own to moisturize skin. It’s cheap. It’s unscented. It seems to work well for softening skin, so what could be the problem?
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What is Petroleum Jelly?
Petroleum jelly is a byproduct of the oil refining process. This means it is not sustainable or eco-friendly, and it also explains some of the potential problems with using it.
Petroleum jelly was originally found in the bottom of oil rigs and is further refined for use in the beauty industry. According to packaging and safety info, all of the harmful components are removed before use in beauty or personal care products, but some sources argue that it still contains some harmful components (like hydrocarbons).
How Does Petroleum Jelly Work on Skin?
Petroleum jelly is used in everything from lotions to baby products for its ability to create a protective barrier on the skin and hold in moisture. On labels, it may also appear as Petrolatum, Mineral Oil, Liquid Paraffin, or Paraffin Oil.
While the ability to hold in moisture may seem like a good thing, it can have its downsides as well. Since petroleum jelly is both waterproof and not water soluble, it creates a waterproof barrier on the skin.
At first glance, this may sound good, but it also means that it blocks pores and can lock in residue and bacteria. This is also the reason petroleum jelly should not be used on a burn or sunburn, as it locks in heat and can block the body’s ability to heal.
Also, while it certainly gives the appearance of hydrated and moisturized skin, this may be an illusion as there is nothing in petroleum jelly that is actually nourishing the skin. If you are looking for something to help hold in moisture and nourish the skin, some natural products accomplish both (see the end of this post for a list).
Problems with Petroleum Jelly
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Besides its pore-blocking potential, petroleum jelly carries some potentially bigger problems as well.
Petroleum jelly can’t be metabolized by the skin and just sits as a barrier until it wears off. This means that the body isn’t able to gain any benefit from petroleum jelly (like it can from nutrient rich substances like shea butter or cocoa butter), and there is concern that some of the components (like hydrocarbons) may be stored in fat tissue within the body.
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In fact, a 2011 study found that:
There is strong evidence that mineral oil hydrocarbons are the greatest contaminant of the human body, amounting to approximately 1 g per person. Possible routes of contamination include air inhalation, food intake, and dermal absorption.
This study was interesting because it evaluated both the long-term storage potential of these hydrocarbons in the body and also a woman’s ability to pass them on to her child through breastfeeding. It looked at fat tissue samples obtained from women during a c-section and a follow-up of breast milk samples and found a strong correlation between the amounts of fat tissue and the amounts passed on in breastmilk.
This suggests the potential for long-term accumulation of these hydrocarbons in the body. The study found no link between nutritional habits and hydrocarbon levels in the body but did find a strong potential link between cosmetic and beauty product use and contamination, suggesting that beauty products may be a major source of hydrocarbon exposure.
As moms, this study is especially interesting, since it shows the potential for passing on these contaminants to our children during breastfeeding. We also know that we can’t metabolize these substances, so they can build up in the body and are difficult to remove.
Because of the barrier that mineral oil/petroleum jelly creates on the skin, there is also some concern about its potential to cause collagen breakdown (the opposite of what most women want).
Essentially, the concern is that when petroleum jelly coats the skin, it blocks the skin’s natural ability to breathe and absorb nutrients. This can slow the cell renewal process and cause the skin to pull the necessary moisture and nutrients from within, leading to collagen breakdown over time (aka wrinkles!).
A growing problem in today’s world, estrogen dominance is when the body has high levels of estrogen and proportionately low levels of progesterone to balance it. It is linked to infertility, menstrual problems, accelerated aging, allergies, and autoimmune problems as well as nutrient deficiencies, sleep problems and even some types of cancers.
Many products (including petroleum jelly) contain chemicals called xenoestrogens, which may increase estrogen problems in the body. Studies have shown that these chemicals may act on hormone receptors in the body and lead to estrogen dominance.
More Serious Problems
There is the potential that petroleum based products contain other harmful chemicals like 1,4 dioxane, a known carcinogen found in almost a quarter of all beauty products tested.
Additionally, as drug commercials like to warn us, “other more serious complications may occur.” While more severe problems are rare, they can happen, and the statistics don’t matter if you are the 1% that ends up with the problem (though to put it in perspective, it is probably about the chance that you actually have liver cancer due to the skin rash you searched for on WebMD).
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One of these serious problems is called lipid pneumonia. Though rare, this occurs when small amounts of the petroleum jelly are inhaled and build up in the lungs (as mentioned earlier, the body can’t metabolize or break down petroleum jelly). This creates a potentially severe inflammation of the lungs.
Alternatives To Petroleum Products for the Skin
Thankfully, there are many great alternatives to petroleum jelly and mineral oil that help increase moisture on the skin and provide nourishment as well. The best part? Most of them can be used alone, and you don’t even have to make anything!
If you are looking for a simple alternative to petroleum jelly or Vaseline®, try:
- Shea Butter – A natural skin superfood that is high in Vitamins A, E, and F. It also contains beneficial fatty acids that nourish skin and it may reduce skin inflammation and increase collagen production. It is excellent on its own or in homemade beauty products. (This is the one I like).
- Cocoa Butter – A great source of antioxidants and beneficial fatty acids, cocoa butter is another great product for skin. There is even some evidence that it may reduce the signs of aging. (This is the brand I’ve used)
- Beeswax – A great substitute for the waterproof and protective properties of petroleum jelly without the hydrocarbons. Though not usually used alone, beeswax can be blended into homemade beauty products for its skin-protective ability and is especially useful in lip balms and body creams.
- Coconut Oil – Coconut oil has so many benefits, internal and external, and it can be great for the skin. It does cause breakouts in some people, so I always suggest testing on a small area of skin first, but it is a source of skin-nourishing fatty acids, lauric acid, and anti-inflammatory compounds.
- Almond Oil – A liquid oil that is fragrance-free and nourishing to the skin.
- Jojoba Oil – A perfect choice for skin care because it naturally resembles sebum, the oily substance naturally produced by the body to nourish and protect skin. I like to mix Jojoba Oil with Shea butter for a simple natural lotion.
Petroleum Jelly Free Skin Recipes
If you’re feeling crafty, there are a lot of great skin-nourishing recipes that you can make using the simple ingredients above:
- Simple Oil-Based Lotion
- Whipped Body Butter
- Soothing Skin Salve
- Easy to use Lotion bars
- Eczema Relief Lotion Bars
- Magnesium Body Butter
- Lip Salve
- Gardeners Hand Salve
- Peppermint Lip Balm
The Bottom Line
I’ve never been a fan of petroleum jelly (or Vaseline®) because every time I’ve tried it, my naturally oily skin went crazy and I had breakouts for at least a week. Since there are many potential problems with using it and a variety of great natural alternatives, I’m glad it is a product I never actually started using.
Do you use petroleum jelly? Have you switched to these alternatives instead?
Here’s one more great alternative – Homemade Rub For Colds and Skin Problems!
Adams, R. (2013, October 21). Petroleum Jelly May Not Be As Harmless As You Think. Retrieved from http://www.huffingtonpost.com/2013/10/21/vaseline-petroleum-jelly_n_4136226.html
Concin, N., Hofstetter, G., Plattner, B., Tomovski, C., Fiselier, K., Gerritzen, K., . . . Grob, K. (2011, November). Evidence for cosmetics as a source of mineral oil contamination in women. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/21970597
Vrabie, C. M., Candido, A., Van, M. B., & Jonker, M. T. (2010, July). Specific in vitro toxicity of crude and refined petroleum products: II. Estrogen (alpha and beta) and androgen receptor-mediated responses in yeast assays. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/20821602
Environmental Working Group. (2007, February 8). EWG Research Shows 22 Percent of All Cosmetics May Be Contaminated With Cancer-Causing Impurity. Retrieved from http://www.ewg.org/news/news-releases/2007/02/08/ewg-research-shows-22-percent-all-cosmetics-may-be-contaminated-cancer
Brown, A. C., Slocum, P. C., Putthoff, S. L., Wallace, W. E., & Foresman, B. H. (1994, March). Exogenous lipoid pneumonia due to nasal application of petroleum jelly. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/8131586
Vasil, A. (2013, February 21). Can you recommend alternatives to petroleum jelly? Retrieved from https://nowtoronto.com/lifestyle/ecoholic/can-you-recommend-alternatives-to-petroleum-jelly/
Serum Ferritin and GGT — Two Potent Health Indicators You Need to Know
- By monitoring your serum ferritin (stored iron) and GGT levels and taking steps to lower them if they’re too high, you can avoid serious health problems
- Virtually all adult men and postmenopausal women are at risk for iron overload due to inefficient iron excretion. Left untreated, it can contribute to cancer, heart disease, neurodegenerative diseases and other chronic health problems
- GGT is a liver enzyme involved in glutathione metabolism and the transport of amino acids. GGT can be used as a screening marker for excess free iron and is a potent predictor of mortality
By Dr. Mercola
While many health screens and lab tests are overrated or unnecessary, there are a few that are vitally important, such as vitamin D. I recommend checking your vitamin D level at least twice a year.
Two other really important tests are serum ferritin (which measures stored iron) and gamma-glutamyl transpeptidase or sometimes called gamma-glutamyltransferase (GGT; a liver enzyme correlated with iron toxicity, disease risk and all-cause mortality). By monitoring your serum ferritin and GGT levels and taking steps to lower them if they're too high, you can avoid serious health problems.
For adults, I strongly recommend getting a serum ferritin test and GGT on an annual basis. When it comes to iron overload, I believe it can be every bit as dangerous to your health as vitamin D deficiency. In this interview, Gerry Koenig,1 former chairman of the Iron Disorders Institute and the Hemochromatosis Foundation, explains the value of these two tests.
Iron Overload Is More Common Than Iron Deficiency
Iron is one of the most common nutritional supplements. Not only can you get it as an isolated supplement, but it's also added to most multivitamins. Many processed foods are also fortified with iron. While iron is necessary for biological function, when you get too much, it can do tremendous harm.
Unfortunately, the first thing people think about when they hear "iron" is anemia, or iron deficiency, not realizing that iron overload is actually a more common problem, and far more dangerous. Many doctors don't understand or appreciate the importance of checking for iron overload.
Virtually all adult men and postmenopausal women are at risk for iron overload due to inefficient iron excretion, since they do not lose blood on a regular basis. Blood loss is the primary way to lower excess iron, as the body has no active excretion mechanisms. Another common cause of excess iron is the regular consumption of alcohol, which will increase the absorption of any iron in your diet.
For instance, if you drink wine with your steak, you will likely absorb more iron than you need. There's also an inherited disease, hemochromatosis, which causes your body to accumulate excessive and dangerously damaging levels of iron.
If left untreated, high iron can contribute to cancer, heart disease, diabetes, neurodegenerative diseases and many other health problems, including gouty arthritis. In one small study,2 100 percent of the patients achieved marked reduction in attacks or complete remission after phlebotomy was used to remove iron and maintain an iron level at near-iron deficiency — "the lowest body iron store compatible with normal erythropoiesis and therefore absence of anemia."
Iron causes all this harm by catalyzing a reaction within the inner mitochondrial membrane. When iron reacts with hydrogen peroxide, hydroxyl free radicals are formed. These are among the most damaging free radicals known, causing severe mitochondrial dysfunction, which in turn is at the heart of most chronic degenerative diseases.
GGT Is a Potent Predictor of Mortality
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GGT is a liver enzyme involved in glutathione metabolism and the transport of amino acids and peptides. Not only will the GGT test tell you if you have liver damage, it can also be used as a screening marker for excess free iron and is a great indicator of your sudden cardiac death risk.
In recent years, scientists have discovered GGT is highly interactive with iron, and when both your serum ferritin and GGT are high, you are at significantly increased risk of chronic health problems, because then you have a combination of free iron, which is highly toxic, and iron storage to keep that toxicity going.3
"Recently, [GGT] was proven by the life insurance industry as the single measure that is most predictive of early mortality,"4,5 Koenig says. "In other epidemiological studies, it's linked to pretty much every cause of death,6 because it provides those free radicals and hydroxyl radicals …
I believe that … people born after World War II are now at greater risk because of the environmental toxicants we face … Basically, reduction in glutathione levels — your body's most important antioxidant — is indicated by an increase in GGT …
[G]lyphosate, excess iron, all of the substances in the environment — whether you take it in as food or it's in the air — that utilize your body's toxic waste disposal system in some way [will] reduce your antioxidants, whether it's vitamin D, cholesterol, vitamin E or vitamin A. A reduction of those makes you more vulnerable to disease, particularly chronic disease and autoimmune diseases across the board."
Ideal GGT and Iron Levels
As with many other lab tests, the "normal" ranges for GGT and serum ferritin are far from ideal.7 If you're in the "normal" range, you're virtually guaranteed to develop some sort of health problem. Based on Gerry's recommendation I had my GGT tested last month and it was 17, which is healthy especially since my ferritin level is 37. You really need both tests to confirm lack of iron toxicity as he explains in the full interview.
Ideal GGT Level, units per liter (U/L)
Average level, above which your risk for chronic disease increases significantly
"Normal" GGT Level8
Less than 16 U/L
Up to 70 U/L
Less than 9 U/L
Up to 45 U/L
According to Koenig, women with a GGT above 30 U/L have a higher risk of cancer and autoimmune disease. Interestingly, while for most other tests the range between what's healthy and what's risky tends to be quite broad, in the case of GGT, the range between health and disease is in the single digits.
"Part of it is dependent on body weight," Koenig says. "Strangely enough, the most recent indications are that people who are too thin (whatever their level of GGT is), it could be harmful if [their GGT is] relatively high.9 For instance, for a thin woman with a GGT … in the range of the second quartile, which is going to be generally 14 to 18 today it can be dangerous if she's expecting to have children and has a very low BMI."10
When it comes to serum ferritin, a level of 200 to 300 nanograms per milliliter (ng/mL) falls within the normal range for women and men respectively, which is FAR too high for optimal health. An ideal level for adult men and non-menstruating women is somewhere between 30 and 60 ng/mL.
You do not want to be below 20 ng/mL or above 80 ng/mL. The most commonly used threshold for iron deficiency in clinical studies is 12 to 15 ng/mL.11 Maintaining a healthy iron level is also important during pregnancy. Having a level of 60 or 70 ng/mL is associated with greater odds of poor pregnancy outcomes.12 That said, iron deficiency during pregnancy is equally problematic, so make sure you get tested.
Last but not least, since the ferritin and GGT are interactive, low GGT tends to be protective against higher ferritin. So, if your GGT is low, you're largely protected even if your ferritin is a bit higher than ideal. Still, it would be wise to take steps to lower your ferritin to a more ideal level nonetheless. On the other hand, even if your ferritin is low, having an elevated GGT levels is cause for concern, and needs to be addressed.
When Might a Transferrin Saturation Test Be Useful?
If you are thin, with a body mass index (BMI) below 22 or 23, Koenig suggests getting a transferrin test as well, which gives you a percentage saturation level. A level of 25 to 35 percent is typically considered healthy. In the 1970s, the transferrin saturation test was used as a marker for early death. Having a transferrin saturation percentage of over 55 indicated a 60 percent increased risk for premature death.
At that time, an estimated 2.6 percent of the U.S. population had transferrin saturation percentages that high. Today, it's down to half of that, in large part because of the increase in obesity, which "dilutes" your saturation percentage, and the transferrin test is no longer used as a marker for early death. However, if you are very thin, it can still be a useful test.
"Anything between 25 and 35 is safe. If you're unusually thin, I would get that test because there you could have unsuspectingly high transferrin saturation, particularly if you're malnourished … Anorexia nervosa has severe effects on the brain when you're that thin and your BMI is at 14 or 15," Koenig says.
Why Excess Iron Is so Dangerous
Your body creates energy by passing the electrons from carbs and fats you eat as fuel to oxygen through the electron transport chain in your mitochondria to produce adenosine triphosphate (ATP). Ninety-five percent of the time, the oxygen is converted to water. But 0.5 to 5 percent of the time, reactive oxygen species (ROS) are created. ROS are not all bad as they are important biological signaling molecules, but excessive ROS leads to mitochondrial damage and dysfunction.
Iron can react with hydrogen peroxide in the inner mitochondrial membrane. This is a normal part of cellular aerobic respiration. But when you have excessive iron, it catalyzes the formation of excessive hydroxyl free radicals from the peroxide, which decimate your mitochondrial DNA, mitochondrial electron transport proteins and cellular membranes. This is how iron overload accelerates chronic disease.
If you eat excessive net carbs (total carbs minus fiber) the situation is further exacerbated, as burning carbs as your primary fuel can add another 30 to 40 percent more ROS on top of the hydroxyl free radicals generated by the presence of high iron.
Unfortunately, most people reading this are burning carbs as their primary fuel. If you struggle with any kind of chronic health problem and have high iron and eat a standard American diet that is high in net carbs, normalizing your iron level (explained below) and implementing a ketogenic diet as described in my book, "Fat for Fuel," can go a long way toward improving your health.
Taking extra antioxidants to suppress ROS generated by high iron alone or in combination with a high-sugar diet is inadvisable, as ROS also act as important signaling molecules. They're not all bad. They cause harm only when produced in excess.
Your best bet is to lower the production of ROS. One of the easiest and most effective ways to do that is to eat a diet high in healthy fats, adequate in protein and low in net carbs. Eating healthy fats can make a bigger difference than you might think, especially if you have high iron.
How to Lower Your Iron
The good news is it's easy to lower your iron level if it's too high. One of the easiest ways is simply to donate blood two or three times a year. If you have severe overload you may need to do more regular phlebotomies. Two years ago, my ferritin was 150 ng/mL. I implemented self-phlebotomy where I would take out anywhere from 2 to 6 ounces of blood every few weeks, which brought me below 100 ng/mL.
I stopped the phlebotomy when I started a comprehensive detoxification strategy involving near and far infrared sauna, and interestingly, despite the fact I was no longer removing blood, my ferritin continued to drop over the next nine months. Now, it's down to 37 — far lower than I was ever able to get down to with therapeutic phlebotomies, and as I mentioned earlier I have a healthy GGT level of 17.
As it turns out, an effective detoxification program can lower iron as well. While this was a surprise to me, Koenig confirms that this has indeed been documented by Dr. F.S. Facchini in some of his research on iron. While I've long recommended donating blood as the solution to iron overload, I now believe a balanced approach using phlebotomy, detoxification and reducing dietary iron, especially meat, is the best way to go about it.
Keep in mind that trying to control high iron through your diet alone can be risky, as you will also forgo many valuable nutrients. That said, to avoid maximizing iron absorption, avoid eating iron-rich foods in combination with vitamin C-rich foods or beverages, as the vitamin C will increase iron absorption. If needed, you could also take a curcumin supplement. Curcumin acts as a potent chelator of iron and can be a useful supplement if your iron is elevated.
How to Lower Your GGT
GGT is inversely related to glutathione, a potent antioxidant produced in your body. As your GGT level rises, your glutathione goes down. This is part of the equation explaining how elevated GGT harms your health. By elevating your glutathione level, you will therefore lower your GGT. The amino acid cysteine, found in whey protein, poultry and eggs, plays an important role in your body's production of glutathione.
Red meat, which does not contain cysteine, will tend to raise GGT, as will alcohol, so both should be avoided.13 Research also suggests eating at least 10 servings of fruits and vegetables rich in in vitamin C, fiber, beta-carotene, anthocyanins and folate per week can help reduce GGT.14,15 Examples include carrots, romaine lettuce, spinach, sweet potatoes, apricots and tomatoes.
Also, be aware that certain medications can raise your GGT. If this is the case, please confer with your doctor to determine whether you might be able to stop the medication or switch to something else, and avoid over-the-counter medicines, including ibuprofen and aspirin, both of which can damage your liver.
General detoxification is another important component if your GGT is high, as your liver's job is to remove toxins from your body. The fact that your GGT is elevated means your liver is under stress.
The Protein-Iron-GGT Connection
I personally typically eat only 2 to 4 ounces of meat per week Americans tend to overeat meat in general, and most of it is dangerous CAFO meat loaded with toxins. Additionally, while the meat supplies you with more iron than you likely need, excess protein can also cause problems. Another little-known fact is that giving iron to a person who is malnourished and cannot process protein properly can be extremely dangerous. Koenig explains:
"I've been studying malnutrition for several years now, mainly kwashiorkor (also known as protein-calorie malnutrition), which is a typical malnutrition disease, along with marasmus in developing countries. There you have a situation where the children, particularly in kwashiorkor, cannot synthesize important proteins because of essential amino acid deficiencies …
[When] giving iron too early in a recovering child with kwashiorkor, or an adult for that matter, the measure that skyrockets early on, in that particular case, happens to be GGT.
High amounts of free iron [are dangerous] because they don't have the proteins to safely contain that iron into either transferrin, which is the protein that protects the body from the iron in the bloodstream, or ceruloplasmin, which is necessary for copper transport. To get iron safely into the brain, it needs to be complexed with ceruloplasmin. Those can't be synthesized in a malnourished person. [So, giving] iron to a malnourished person is highly toxic."
African and Chinese Research Confirm GGT's Relation to Chronic Disease
Koenig recently found a few African studies showing the importance of GGT. In the 1990s, when GGT was tested broadly in the U.S. as part of the National Health and Nutrition Examination Survey III (NHANES III, 1988 to 1994), results revealed that African-Americans had higher levels of both serum ferritin and GGT than Caucasians and Hispanics.
"Back then, those measurements were compared to measurements in Zimbabwe. In [Zimbabweans] who were not exposed to spraying for mosquitoes … the [ferritin and GGT measurements] were roughly half.
They had obviously been on a native diet … But I found, through several papers recently submitted in South Africa, that those measurements now are very high. They're catching up and probably surpassing the American Blacks' measurements, and they're suffering the [same] chronic diseases …"
More recent studies from South Africa depict increasing GGT levels are associated with insulin resistance and cardiometabolic disease risk.16 Moreover, a recent Chinese study showed that while having a GGT level above the midpoint raised the risk of chronic kidney disease, when combined with high serum ferritin, that risk increased nearly fivefold.17 Other common diseases associated with high iron and GGT include diabetes, heart disease and cancer.
Blood Donations Lead to Radical Reduction in Disease
A number of epidemiological studies have also documented a significant reduction in chronic diseases among those who donate blood two or three times a year — findings that support the notion that iron overload is prevalent, and contributes to chronic disease. In some, heart disease and cancer were reduced by as much as 50 percent, Koenig notes.
Unfortunately, many doctors are still unaware of the importance of checking for iron overload (based on ideal levels and not what's considered normal), and may overlook the GGT test as well.
"One of the reasons it's difficult to get doctors to order GGT tests is they're discouraged because they know some prescription drugs increase [GGT]. Although the overall effect may be protective, it's not a happy situation to see a measure of disease increase just by taking a drug. There's resistance in that area of getting tested. But it's a pretty simple test. It would be recommended. And blood donation basically keeps one healthy," Koenig says.
In summary, if you're concerned about maintaining your health and preventing chronic disease, I would strongly encourage you to get a ferritin and a GGT test regularly, and if needed, implement the strategies discussed above to get them into their optimal ranges.
Serum ferritin and GGT are markers for iron toxicity, which is a major mostly unrecognized contributor to heart disease, cancer, diabetes, nonalcoholic fatty liver disease and many other chronic diseases. High iron even increases your risk of infections. As noted by Koenig, you really don't want to check into a hospital with high iron, as your risk of contracting a hospital-acquired infection will be that much greater. The good news is, it's so easy to turn around, thereby dramatically reducing your risk.
To learn more, I recommend visiting HealtheIron.com, where you can also order your serum ferritin and GGT tests or either of their special FeGGT-LifePRO™ test panels. If either serum ferritin or GGT is elevated, you need to take action. The treatment couldn't be simpler. Unless you're a menstruating woman, simply donate blood two to three times a year. If you do not qualify to donate blood, ask your doctor to write you a prescription for therapeutic phlebotomy.
Tuesday, September 19, 2017
The 7 most common toxins people apply to their skin DAILY without even knowing it
Monday, September 18, 2017 by: S.D. Wells
Tags: Chemical exposure, parabens, Personal care products, petroleum, phthalates, skin care, skin care producsts, toxic chemicals, toxic cosmetics, toxic ingredients, toxic makeup, triclosan, triclosan toxic
Tags: Chemical exposure, parabens, Personal care products, petroleum, phthalates, skin care, skin care producsts, toxic chemicals, toxic cosmetics, toxic ingredients, toxic makeup, triclosan, triclosan toxic
(Natural News) It’s so easy to say you are living a healthy life when you are safeguarding what you eat and drink, trying to stick to mostly organic and raw whole foods, but millions of Americans often forget the fact that their skin is their largest organ, and most body care products are loaded with allergens, irritants and carcinogenic chemicals that are easily absorbed by their porous skin and thus enter the blood and lymphatic system. Never underestimate how easily chemicals we breathe in or put on our skin have just as much effect on our health as what we consume.
What’s worse is that the personal care products industry as a whole has virtually no regulations or inspections from the FDA, so companies and corporations literally “get away with murder” regarding a slow poisoning of people who don’t pay attention to ingredients or know the names of the “repeat offenders” that are found in thousands of products.
You won’t believe how fast and easily the skin absorbs dangerous chemicals. Skin absorption rates for chemicals were tested and published in the American Journal of Public Health. Fragrance ingredients are absorbed at an astonishing 100 percent rate. Your face, underarms and genitalia are also much more vulnerable to absorbing toxins than other broader body surfaces, so be extra careful when inspecting ingredients in soaps, cosmetics, deodorants, antiperspirants and powders. Take extra special care to inspect baby products also, which are barely regulated at all for health safety. Here are some rules of thumb to abide by when selecting body care products.
If you cannot pronounce an ingredient and you would not eat it, you probably should NOT put it on your skin, hair, lips or fingernails
Do the ingredient lists in most body care products you buy look like formulas for chemistry class experiments? You may be wondering how the heck these ingredients are supposed to help you take care of your body, and that’s because they don’t. Fancy words like preservatives, additives, fragrances, emulsifiers, conditioners, smoothing agents, straightening agents and derivatives might simply mean YOU and your children are the guinea pigs for untested, unregulated chemistry experiments, and you could wind up in a laboratory being studied for some disease or disorder the doctors and scientists just can’t seem to “find a cure” for at all.
Here are some common chemicals you may find in the cocktails and concoctions sold as “all natural” or “pure and natural.” Some corporations and companies that brag about using organic ingredients will still add in other chemicals and toxic agents that lead to health problems, so you really have to read the entire ingredients list carefully and be your own filter. Some products will brag about not containing two or three popular toxins, but then still include plenty of other carcinogens. Watch out for these body care “criminals:”
- Sodium Luaroyl Sarcosinate
- Sodium Lauryl Sulfate (SLS)
- Sodium Laueth Sulfate (SLES)
- Tocopheryl acetate
- Cocoamidopropyl Betaine
- Olefin Sulfonate
- Petroleum and petroleum-based derivatives (industrial chemicals often listed as coloring and dyes)
- Disodium EDTA
- BHT (butylated hydroxytoluene)
- Titanium dioxide
- Iodopropynyl buutylcarbamate
- Polyisobutene (a synthetic polymer)
- Cocamide DEA
- MIT (Methylisothiazolinone)
The Cosmetic “Dirty Dozen” – Beautifying ingredients that aren’t very “pretty” at all
One out of every eight beauty product ingredients are actually industrial chemicals. This means if you put them on your skin, hair, lips or fingernails, your body will be absorbing pesticides, hormone disruptors, reproductive toxins, plasticizers, surfactants, paints, inks, degreasers and other cancer-causing agents. A U.S. researchers report on toxic beauty product ingredients found that at least 80 percent of cosmetics contain at least one of the following toxic chemicals:
– BHA and BHT (often found in makeup and moisturizers)
– Coal tar dyes listed as “CI” with a five digit number (watch for p-phenylenediamine and FD&C Blue No. 1)
– DEA, MEA and TEA – chemicals that are already proven harmful to fish and wildlife (remember humans are animals too)
– Dibutyl phthalate (check your nail care products)
– Formaldehyde (embalming fluid for the dead) and Urea (animal urine that slowly releases formaldehyde) “preservatives”
– Parfum or fragrance (also listed as “unscented”) – linked to asthma, allergies, neurotoxic effects and cancer
– PEG compounds (may include 1,4-dioxane cancer-causing ingredient and/or propylene glycol)
– Petrolatum (could be contaminated with cancer-causing polycyclic aromatic hydrocarbons or “PAHs”)
– Siloxanes and Methicones (used for smoothing, softening and moisturizing agents)
– Sodium Laureth (or Lauryl) Sulfate (foaming agent for shampoos, bubble bath, cleansers and cosmetics often contaminated with 1,4-dioxane)
– Triclosan (often found in toothpastes, antiperspirants, cleansers) – contributes to antibiotic resistant bacteria and can be an endocrine disruptor for humans.
Just how many of the 7 most common body care toxins are YOU using daily?
#1. Antibacterial hand cleansers (destroys good bacteria too)
#2. Talc (baby powder, foot powder, body powder)
#3. Petroleum (common lip balms, baby oils and Vaseline)
#5. Sodium lauryl sulfate
#7. Lead (common in lipstick)
Learn more about the ingredients in the products you use at Cosmetics.news.
Sources for this article include:
Our Bodies Are Becoming Plastic
- Globally, 83 percent of tap water samples tested were found to contain tiny microplastic particles
- In the U.S., 94 percent of tap water samples were found to contain plastic — the most out of all the locations tested
- Large quantities of microplastics are likely being transferred to agricultural land via sewage sludge
How University Foundations Circumvent Conflict of Interest Disclosure Rules and Hide Corporate Ties to Faculty
By Dr. Mercola
It was a sad day in October 2015 when researchers from the Alfred Wegener Institute, Helmholtz Centre for Polar and Marine Research (AWI) announced they had detected plastic litter on the surface of Arctic waters.1 Greenland sharks and seabirds living in the area were already known to be eating the debris,2 but the appearance of 31 pieces of floating debris in an otherwise largely pristine environment painted a disturbing picture of pollution problems that will only get worse if the amounts of litter entering the oceans aren’t reduced.
With plastics now entering the farthest reaches of the globe, what does that mean for the environments where these pollutants are known to accumulate? Mismanaged waste is particularly problematic in China, Indonesia, Vietnam, Thailand and the Philippines, which together make up the top five countries for plastic pollution.3 In the U.S., one of the top waste-generating countries, littering is a major issue, especially in the form of single-use plastics, like soda bottles, drinking straws and potato chip bags.
According to environmental advocacy group Ocean Conservancy, some plastic products persist for so long, even in salty ocean water, that they’ll still be recognizable after 400 years.4 However, an equally alarming problem is the plastics that do get broken down into tiny pieces. Microplastic particles, which are less than 5 millimeters long, are literally clouding the oceans in spots.
Carried along with the ocean’s currents, swirling gyres of “plastic smog”5 now cover about 40 percent of the world’s ocean surfaces.6 They’re being eaten by fish and other marine life — that is well-known. But only recently did researchers take the logical next step to determine that it’s not only marine life ingesting plastic — you probably are too.
94 Percent of US Tap Water Contains Plastic Fibers
Research commissioned by media outlet Orb revealed alarming data about plastic pollution in tap water, with 83 percent of samples tested worldwide coming back as contaminated. In the U.S., 94 percent of tap water samples were found to contain plastic — the most out of all the locations tested. According to Orb:7
“Fibers in tap water … are both a discovery and a marker — a visceral sign of how far plastic has penetrated human life and human anatomy. We can't see the long-chain molecules of pollutants like polyfluoroalkyl chemicals, even if they do reside in more than 98 percent of the population. But when fibers are filtered in a laboratory and enlarged by a microscope, the contamination becomes real.
The first studies into the health effects of microscopic plastics on humans are only just now beginning; there’s no telling if or when governments might establish a ‘safe’ threshold for plastic in water and food. Even farther away are studies of human exposure to nanoscale plastic particles, plastic measured in the millionths of a millimeter.”
Orb found, for example, 16 fibers in tap water taken at the visitor’s center in the U.S. Capitol in Washington, D.C., along with fibers in samples taken from Trump Tower in New York. Plastic fibers were also found in water taken from Indonesia, India, Ecuador, Uganda, England and Lebanon.
Where Are the Primary Sources of Microplastic?
Orb noted six primary sources of “invisible plastics,”8 one of which is synthetic microfibers from synthetic clothing like fleece, acrylic and polyester. Microfibers from clothing are released during washing, to the tune of 1 million tons a year. It’s unknown what the environmental effects of microfiber pollution may be, but their irregular shape may make them harder for marine life to excrete than other microplastics (like microbeads).
According to the Mermaids (Mitigation of Microplastics Impact Caused by Textile Washing Processes) project, whose goal is to cut microfiber shedding during washing by 70 percent, the apparel industry has been slow to respond in taking steps to stop microfiber pollution.9
A Mermaids report suggested special coatings may help to stop the loss of microfibers during washing, as well as recommended laundry detergents be reformulated to minimize fiber shedding. However, as it stands Orb estimated that more than half of the microfibers released during the wash are missed by water treatment plants and end up in the environment.
Microbeads — those tiny plastic pellets you may have seen in your face wash or hand soap — are another primary source. Microbeads are so small they get flushed right down the bathroom drain and travel through wastewater treatment plants easily, because the filters used are too small to catch them. Research has only begun to reveal the extent of environmental pollution that microbeads have caused.
In a 2012 survey of the Great Lakes, it was found that the area has “some of the highest concentrations of microplastic found in the environment, and microbeads were prevalent.”10 One-third of the fish caught in the English Channel also contain microbeads, as do 83 percent of scampi sold in the U.K. 11 Bans on microbeads have taken place in the U.S. and Canada, but not yet in the EU. Orb estimated that more than 8 trillion microbeads ended up in U.S. waterways in 2015. Other sources noted in Orb’s report include:12
- Tire dust, which contains styrene butadiene rubber. According to Orbit, “Cars and trucks emit more than 20 grams of tire dust for every 100 kilometers they drive.”13
- Paints: Microplastics are distributed in paint dust, which comes from house paint, ship paint, road markings and more.
- Secondary microplastics: Single-use plastics like forks, bags, straws and takeout containers also litter the environment, with 8 million tons washing into waterways each year. Eventually, these items get broken down into microplastics.
- Airborne plastic fibers: This is a new area of research, but it’s thought that your limbs brushing against each other may be enough to release synthetic fibers into the air, which can be inhaled as well as float down to further contaminate the environment. In Paris, airborne microplastics have been found to fall to the ground at rates of up to 10 tons a year.14
Toxic Microplastics May Be Transferred to Farmland
Much of the research on microplastic pollution focuses on marine environments, but the toxic bits are also likely accumulating on land. According to research published in Science of the Total Environment, “Annual plastic release to land is estimated at four to 23 times that released to oceans.”15 The use of sewage sludge, or biosolids, as fertilizer may be particularly problematic. It’s basically made up of whatever’s left over after sewage is treated and processed.
Writing in Environmental Science & Technology, researchers reported that in Europe and North America, about 50 percent of sewage sludge is used for agricultural purposes. Using data from farm areas, population and sewage sludge usage, along with microplastic emission estimates, they found that between 125 and 850 tons of microplastics per million inhabitants may be added to European agricultural soils each year.
When factoring in the range of sludge application rates, and assuming data from certain other countries with similar plastics usage are comparable, the study found a “total yearly input of 63,000 to 430,000 and 44,000 to 300,000 tons of microplastics to European and North American farmlands, respectively …
This would be an alarmingly high input,” the researchers noted. “Comprehensively, this exceeds the total accumulated burden of 93,000 to 236,000 tons MPs [microplastics] currently estimated to be present in surface water in the global oceans.”16 In a related publication, the researchers called for an urgent investigation to “safeguard food production,” considering the finding that large quantities of microplastics are likely being transferred to agricultural land via sewage sludge.17,18
Plastic Particles Smell Like Food to Fish
It’s long been known that fish are eating plastic debris, but a disturbing study revealed this isn’t occurring by happenstance. Instead, fish may be actively seeking out plastic particles in the ocean to eat, mistaking them for food because of their odor. When microplastics exist in the ocean, they form a biological covering made of algae and other materials that smell like the food the fish would normally eat.19
The study is the first to reveal not only that anchovy use odors to forage, but also that the odor of microplastic in the ocean induces foraging behaviors in schools of the fish. The Center for Biological Diversity noted that fish in the North Pacific are known to ingest 12,000 to 24,000 tons of plastic every year and, in a study of fish markets in California and Indonesia, one-quarter of the fish were found to have plastics in their guts.20
Plastics and other man-made debris was also found in 33 percent of shellfish sampled.21 The Orb report even reported that plastic particles less than 50 nanometers long have been shown to collect in plankton, potentially blocking their gastrointestinal tract, as well as accumulating in the many creatures that depend on plankton as a food source. It’s yet another route of plastics exposures to humans, because if the fish are eating plastic, so, too, are the creatures that end up eating the fish.
What effects this will ultimately have on human health remains unknown, but chemical contamination is a real concern. Once in the water, microplastics easily absorb endocrine-disrupting and cancer-causing chemicals like PCBs. Plastics may concentrate such toxins at levels 100,000 to 1 million times higher than the levels found in seawater.22 It’s even possible that plastic particles may end up in places in your body other than your gut. Orb reported:23
“If plastic fibers are in your water, experts say they’re surely in your food as well — baby formula, pasta, soups, and sauces, whether from the kitchen or the grocery. Plastic fibers may leaven your pizza crust, and a forthcoming study says it’s likely in the craft beer you’ll drink to chase the pepperoni down. It gets worse.
Plastic is all but indestructible, meaning plastic waste doesn’t biodegrade; rather, it only breaks down into smaller pieces of itself, even down to particles in nanometer scale — one-one thousandth of one-one thousandth of a millimeter. Studies show particles of that size can migrate through the intestinal wall and travel to the lymph nodes and other bodily organs.”
Become Part of the Solution Instead of Part of the Problem
On a global scale, a variety of endeavors are underway to try to curb plastic waste and pollution. From turning plastic waste into liquid fuel to creating synthetic fibers that don’t shed (or even fashioning clothing out of spider silk), enterprising entrepreneurs are seeking ways to keep plastics out of the environment. Some manufacturers are also looking to create packaging materials that, unlike most packaging currently on the market, can easily be recycled.24
You can also take a stand on an individual level and make a conscious choice to use less plastic. Considering the extensiveness of its use and the way it persists in the environment, plastic has the potential to be the worst environmental disaster of all time. To become part of the solution instead of part of the problem, Orb recommends taking the following steps:25
Avoid plastic bags (including for snacks and food storage)
Avoid disposable straws (reusable straws made from stainless steel, bamboo and even glass are widely available)
Wash synthetic clothes less frequently and when you do use a gentle cycle to reduce the number of fibers released; consider using products that catch laundry fibers in your washing machine
Choose a nonplastic toothbrush made from bamboo, flax or even recycled dollar bills
Avoid disposable plastic bottles; bring your own reusable bottle instead
When washing out paint brushes, capture rinse water in a jar and dispose of it at your local landfill in designated spots for paint (don’t let it go down the drain).
You can also make your own milk paint in lieu of plastic-based latex and acrylics — to do so “add lemon juice to skim milk and filter out the curd, add natural pigment to what is left.”26
Monday, September 18, 2017
Sunday, September 17, 2017
Saturday, September 16, 2017
Boost Brain Function and Blood Flow With This 'Fruit' Extract
Posted on: Saturday, August 24th 2013 at 11:30 am
Written By: Sayer Ji, Founder
This article is copyrighted by GreenMedInfo LLC, 2017
Research confirms the power of a simple dietary change in improving memory problems in middle-aged and older adults.
In a study titled, "Pomegranate juice augments memory and FMRI activity in middle-aged and older adults with mild memory complaints," thirty-two subjects with self-reported memory complaints were randomly assigned to drink 8 ounces of either pomegranate juice or a flavor-matched placebo drink for 4 weeks, receiving memory testing, functional MRI scans (fMRI), and blood draws for peripheral biomarkers before and after the intervention.
After 4 weeks, only the pomegranate group showed significant improvement in verbal memory scores and plasma antioxidant levels. Furthermore, compared to placebo, the pomegranate group showed increased fMRI activity during verbal and memory tasks, indicating pomegranate juice consumption results in increased blood flow to critical task-related brain regions.
This is not the first study to identify a brain-beneficial effect to pomegranate juice, as a sizable body of animal research already exists demonstrating it has neuroprotective properties against aluminum-, stroke-,  and glucose deprivation-associated neurotoxicity, and may also inhibit the formation of pathological plaques and the over-excitation of microglial cells associated with Alzheimer's disease.  
Pomegranate, in fact, is capable of unclogging and tonifying the cardiovascular system, which is especially important when it comes to brain health, and so-called vascular dementia. In fact, in a previous article titled, "How To Clean Your Arteries with One Simple Fruit," I report on the ability of pomegranate juice to regress blockages within the carotid arteries of patients.
There is also its well-known age-defying ability to prevent adverse changes associated with the exhaustion of ovarian function. In a previous article, "Amazing Fact: Pomegranate Can Function as a Back-up Ovary," we looked at animal research explaining how this legendary food, traditionally linked with regeneration and immortality, may provide an alternative to bioidenticial and synthetic hormone replacement therapies.
As the research community continues to explore the potential role of so-called 'medicinal foods' in improving quality of life and preventing and/or treating diseases that are largely refractory to conventional drug-based interventions, we can rest assured that pomegranate will continue to play a central role in the rediscovery of food as medicine.
While much of the research is preliminary, an increasingly robust body of human clinical research indicates that pomegranate has a wide range of potential health benefits, including:
- Improve Pregnancy/Birth Outcomes: Pomegranate juice has been found to potentially protect the unborn fetus by reducing oxidative stress in the placenta.
- Improve Rheumatoid Arthritis: Pomegranate juice reduces disease activity and oxidative stress in rheumatoid patients.
- Improve Heart Disease: Pomegranate juice has been found to have anti-atherogenic properties by reducing oxidative stress, including LDL cholesterol oxidation.
- Fights Prostate Cancer: Pomegranate juice has been found to prolong prostate doubling, as well as inhibit the proliferation and increase programmed cell death in the prostates of men with prostate cancer.
- Contributes to Weight Loss: Pomegranate juice was found to contribute to a reduction in weight, without decreasing insulin sensitivity like other commonly used sources of 'sugar.'
For additional research on pomegranate's wide range of health benefits, visit our pomegranate research page: Pomegranate Health Benefits, wherein you will find primary literature study abstracts on its value in over 100 potential health conditions.
 Ahmed E Abdel Moneim. Evaluating the potential role of pomegranate peel in aluminum-induced oxidative stress and histopathological alterations in brain of female rats. Biol Trace Elem Res. 2012 Dec ;150(1-3):328-36. Epub 2012 Sep 5. PMID: 22945624
 David J Loren, Navindra P Seeram, Risa N Schulman, David M Holtzman. Maternal dietary supplementation with pomegranate juice is neuroprotective in an animal model of neonatal hypoxic-ischemic brain injury. Pediatr Res. 2005 Jun ;57(6):858-64. Epub 2005 Mar 17. PMID: 15774834
 Tim West, Madeliene Atzeva, David M Holtzman. Pomegranate polyphenols and resveratrol protect the neonatal brain against hypoxic-ischemic injury. Dev Neurosci. 2007 ;29(4-5):363-72. PMID: 17762204
 Fatemeh Forouzanfar, Amir Afkhami Goli, Elham Asadpour, Ahmad Ghorbani, Hamid Reza Sadeghnia. Protective Effect of Punica granatum L. against Serum/Glucose Deprivation-Induced PC12 Cells Injury. Evid Based Complement Alternat Med. 2013 ;2013:716730. Epub 2013 Jul 7. PMID: 23935674
 Richard E Hartman, Aartie Shah, Anne M Fagan, Katherine E Schwetye, Maia Parsadanian, Risa N Schulman, Mary Beth Finn, David M Holtzman. Pomegranate juice decreases amyloid load and improves behavior in a mouse model of Alzheimer's disease. Neurobiol Dis. 2006 Dec ;24(3):506-15. Epub 2006 Sep 28. PMID: 17010630
 Soo Jung Choi, Ju-Hyun Lee, Ho Jin Heo, Hong Yon Cho, Hye Kyung Kim, Chang-Ju Kim, Myeong Ok Kim, Soo Hwan Suh, Dong-Hoon Shin. Punica granatum protects against oxidative stress in PC12 cells and oxidative stress-induced Alzheimer's symptoms in mice. J Med Food. 2011 Jul-Aug;14(7-8):695-701. Epub 2011 Jun 1. PMID: 21631359
 Lalida Rojanathammanee, Kendra L Puig, Colin K Combs. Pomegranate polyphenols and extract inhibit nuclear factor of activated T-cell activity and microglial activation in vitro and in a transgenic mouse model of Alzheimer disease. J Nutr. 2013 May ;143(5):597-605. Epub 2013 Mar 6. PMID: 23468550
 Baosheng Chen, Methodius G Tuuli, Mark S Longtine, Joong Sik Shin, Russell Lawrence, Terrie Inder, D Michael Nelson. Pomegranate juice and punicalagin attenuate oxidative stress and apoptosis in human placenta and in human placental trophoblasts. Am J Physiol Endocrinol Metab. 2012 Feb 28. Epub 2012 Feb 28. PMID: 22374759
 Alexandra Balbir-Gurman, Bianca Fuhrman, Yolanda Braun-Moscovici, Doron Markovits, Michael Aviram. Consumption of pomegranate decreases serum oxidative stress and reduces disease activity in patients with active rheumatoid arthritis: a pilot study. Isr Med Assoc J. 2011 Aug ;13(8):474-9. PMID: 21910371
 M Aviram, L Dornfeld, M Rosenblat, N Volkova, M Kaplan, R Coleman, T Hayek, D Presser, B Fuhrman. Pomegranate juice consumption reduces oxidative stress, atherogenic modifications to LDL, and platelet aggregation: studies in humans and in atherosclerotic apolipoprotein E-deficient mice. Am J Clin Nutr. 2000 May ;71(5):1062-76. PMID: 10799367
 Allan J Pantuck, John T Leppert, Nazy Zomorodian, William Aronson, Jenny Hong, R James Barnard, Navindra Seeram, Harley Liker, Hejing Wang, Robert Elashoff, David Heber, Michael Aviram, Louis Ignarro, Arie Belldegrun. Phase II study of pomegranate juice for men with rising prostate-specific antigen following surgery or radiation for prostate cancer. Forsch Komplementmed. 2007 Feb;14(1):39-44. Epub 2007 Mar 6. PMID: 16818701
 Manuel González-Ortiz, Esperanza Martínez-Abundis, María C Espinel-Bermúdez, Karina G Pérez-Rubio. Effect of pomegranate juice on insulin secretion and sensitivity in patients with obesity. Ann Nutr Metab. 2011 ;58(3):220-3. Epub 2011 Jul 28. PMID: 21811060
Sayer Ji is founder of Greenmedinfo.com, a reviewer at the International Journal of Human Nutrition and Functional Medicine, Co-founder and CEO of Systome Biomed, Vice Chairman of the Board of the National Health Federation, Steering Committee Member of the Global Non-GMO Foundation.
Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of GreenMedInfo or its staff.
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